Purification and Characterization of Avian β - Defensin 11 ( AvBD 11 ) : an Antimicrobial 1 Peptide of the Hen Egg . 2 3 Running title : Avian β - defensin 11 , an egg antimicrobial peptide 4 5
نویسندگان
چکیده
منابع مشابه
Multi-function Plant Defensin, Antimicrobial and Heavy Metal Adsorbent Peptide
Background: Defensin peptide isolated from plants are often heterogeneous in length, sequence and structure, but they are mostly small, cationic and amphipathic. Plant defensins exhibit broad-spectrum antibacterial and antifungal activities against Gram-positive and Gram-negative bacteria, fungi and etc. Plant defensins also play an important role in innate immunity, such as he...
متن کاملA Novel Defensin-Like Peptide Associated with Two Other New Cationic Antimicrobial Peptides in Transcriptome of the Iranian Scorpion Venom
Introduction: Scorpion venom is a source of bioactive peptides, and some antimicrobial peptides (AMPs) have been found in the venom gland of scorpions. Therefore, the discovery of new anti-infective agents is an essential need to overcome the problem of antibiotic resistance of clinical isolates. Here, we describe three new cationic AMPs, including meuVAP-6, meuAP-18-1, and meuPep34 from the ve...
متن کاملSoluble fusion expression, characterization and localization of human β-defensin 6.
Human β‑defensin 6 (DEFB106) is an antimicrobial peptide expressed in the epididymis, testis and lung, which indicates that DEFB106 may be involved in innate immunity and fertility. However, as a β‑defensin, this protein has not been well characterized. Using an intein‑mediated fusion expression system, the recombinant DEFB106 was expressed and purified (yield, 3‑5 mg/l) under optimized conditi...
متن کاملθ-Defensins: Cyclic Antimicrobial Peptides Produced by Binary Ligation of Truncated α-Defensins
The first cyclic peptide discovered in animals is an antimicrobial octadecapeptide that is expressed in leukocytes of rhesus monkeys. The peptide, termed rhesus θ-defensin 1 (RTD-1) is the prototype of a new family of antimicrobial peptides, which like the previously characterized αand β-defensin families, possesses broad spectrum microbicidal activities against bacteria, fungi, and protects mo...
متن کاملThe First Salamander Defensin Antimicrobial Peptide
Antimicrobial peptides have been widely identified from amphibian skins except salamanders. A novel antimicrobial peptide (CFBD) was isolated and characterized from skin secretions of the salamander, Cynops fudingensis. The cDNA encoding CFBD precursor was cloned from the skin cDNA library of C. fudingensis. The precursor was composed of three domains: signal peptide of 17 residues, mature pept...
متن کامل